EEFECTS OF VITAMIN A DEFICEINCY ON THE CYTOMORPHOLOGY OF HEPATOPANCREAS OF PARATELPHUSA SPINIGERA WOODMASON

Abstract

The present study was carried out for the first time to analyze the morphological and functional state of hepatopancreas in P. spinigera with different dietary vitamin A level. The study evaluated the growth and changes in the cytomorphology of hepatopancreatic cells. The functional histology was carried out at the (1) Initial period, after (2) 30-35 days, (3) 60-65 days and (4) 90-95 days of administration with control diet. Starting from the early period of deficiency, degeneration of nucleus and haemocytic cells and reduced lumen diameter of the tubules were observed. It has been found that after 90-95 days, the hepatopancreatic epithelium is highly affected and there are several histopathological lesions leading to metaplasia and keratinization of normal columnar epithelium to squamous nature with necrosis of mucous glands.