Synthesis of single crystal 5Bromosalicylaldehyde with Hexamethylenetetramine 5BSHA as anticancer drug.

Authors

  • Ruba.T
  • R. Idamalarselvi
  • S. Sangeetha

Keywords:

Slow evaporation method,

Abstract

In the current effort, 5BSHA crystal development for cancer treatment has been attempted. The slow
evaporation method was first used to create the crystals, and powder X-ray diffraction (XRD) was used
to analyze them. EDAX and FESEM mapping. The phase study was performed using PXRD, and the
results confirmed that the 5BSHA crystals were single phase. The 5BSHA chemical formed in a
Triclinic crystal structure with a space group P, as confirmed by PXRD. Each element's weight
percentage produced the EDX mapping. Additionally, the FESEM morphology analysis revealed that
the 5BSHA crystals were widely distributed and monodispersed. FTIR spectroscopy was used to
confirm the functional groups, while 1HNMR and 13CNMR investigations were used to determine the
molecular structure. It was discovered that 5BSHA crystal may have significant promise for cancer
treatment. The scaffold's in vitro biocompatibility was demonstrated utilizing the MIT Assay with the
Human Liver Cell line HEPG2. has contrasted the other two elements.

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Published

2026-03-21

How to Cite

Ruba.T, R. Idamalarselvi, & S. Sangeetha. (2026). Synthesis of single crystal 5Bromosalicylaldehyde with Hexamethylenetetramine 5BSHA as anticancer drug. The Bioscan, 21(1), 2110–2124. Retrieved from https://thebioscan.com/index.php/pub/article/view/5401