DEVELOPMENT AND EVALUATION OF TERMINALIA CHEBULA HERBAL MOUTHWASH

Abstract

This study investigates the antibacterial potential of Terminalia chebula against
Streptococcus mutans, a primary cause of dental caries. An herbal mouthwash was
formulated using aqueous extracts of T. chebula, honey, and polyethylene glycol.
Phytochemical screening revealed the presence of bioactive compounds like tannins,
flavonoids, and saponins. GC-MS analysis identified a complex chemical profile dominated
by antioxidant-rich compounds, including siloxanes, phosphites, and natural esters. The
formulation exhibited significant antibacterial activity, with Formulation F3 showing
98.88% microbial reduction. The mouthwash demonstrated physical stability over 30 days,
maintaining consistent color, odor, taste, and pH.