Comparative Evaluation of Centesimal and Fifty-Millesimal (LM) Potencies in the Homoeopathic Management of Psoriasis: A Pilot Randomized Controlled Trial

Abstract

Background
Psoriasis is a chronic inflammatory dermatosis with significant physical and
psychosocial burden. Homoeopathy employs individualised prescribing using different
potency scales, most commonly centesimal and fifty-millesimal (LM) potencies.
Comparative clinical evidence between these potency scales remains limited.
Objective
To compare the clinical effectiveness of individualised homoeopathic treatment using
centesimal and LM potencies in patients with psoriasis.
Methods
This study was conducted as a pilot randomized controlled trial at the outpatient
department of Jawaharlal Nehru Homoeopathic Medical College and Hospital. Ten
patients with clinically diagnosed psoriasis were randomly allocated into two parallel
groups: LM potency group (n = 5) and centesimal potency group (n = 5). In both
groups, remedies were selected on an individualised basis according to classical
homoeopathic principles; the potency scale was the only variable. Disease severity was
assessed using the Psoriasis Area and Severity Index (PASI) at baseline and after six
months. Statistical analysis included paired and independent t-tests.