EVALUATION OF AN ISOLATED PHYTOCHEMICAL FROM KIWI FRUIT FOR ITS APOPTOTIC AND CYTOTOXIC EFFECTS ON HEPG-2 LIVER CANCER CELLS

Abstract

Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal forms of liver cancer worldwide, often associated with limited treatment options and poor prognosis. In this study, a phenolic compound, 3',5'-dihydroxy-2'-(methoxy carbonylmethyl)-phenyl-3,4-dihydroxy benzoate, was successfully isolated from the methanolic extract of Actinidia deliciosa (kiwi fruit) and structurally characterized using gas chromatography–mass spectrometry (GC-MS), Fourier- transform infrared spectroscopy (FT-IR), and both proton (^1H) and carbon (^13C) nuclear magnetic resonance (NMR) analysis.