SODIUM FLUORIDE INDUCED HISTOCHEMICAL CHANGES IN THE LIVER OF FRESHWATER FISH, TILAPIA MOSSAMBICA (OREOCHROMIS MOSSAMBICUS)

Abstract

The present investigation deals with the effect of chronic treatment of sodium fluoride, on the histochemical components of the liver from freshwater fish, Tilapia mossambica (Oreochromis mossambicus).This freshwater fish was exposed to the predetermined 1/10th of LC50 concentration (5.4ppm) of sodium fluoride in laboratory conditions for a duration of 10, 20 and 30 days. The histochemical observation revealed that the carbohydrate reserves were severely depleted particularly glycogen as well as increased acidic mucosubstances noticed. This was time dependent to sodium fluoride toxicity. As the fish, Tilapia mossambica is largely consumed by people, it is essential to know the effect sodium fluoride on histochemical changes from liver.