SYNERGISTIC ANTIMICROBIAL ACTIVITY OF EDIBLE HERBS AGAINST MULTI DRUG RESISTANT BACTERIA

Abstract

The antibacterial activity of the two plant extracts and their synergism were studied against some MDR strains. The tested organisms particularly Klebsiella pneumoniae were found to be inhibited by Murraya koenigii extract and also the combination of Murraya koenigii and Coriandrum sativum in comparison to Coriandrum sativum alone. The combinations of the two extracts in various ratios were found to be effective towards MDR strains. On increasing the proportion of the Murraya koenigii and Coriandrum sativum the inhibitory effect increased. The extracts were found to be effective against all the test organisms except Salmonella typhi. MIC was determined by using broth dilution method. The results supported the notion that Synergism of extracts in various ratios is inhibitory towards Multi-drug resistant strains.