Recent Advances in Emulgel-Based Transdermal Drug Delivery Systems for the Management of Fungal Infections

Abstract

Emulgels, which feature dual release control (emulsion and gel), have emerged as one of the most
intriguing topical drug delivery technologies. The physicochemical parameters of the generated
emulgels were assessed, including colour, homogeneity, consistency, spreadability, pH value,
rheological behaviour, drug content, drug release, and stability. They are often used as antiseptics,
antifungal agents, skin emollients, and protective agents. The action of a topical preparation is
determined by a number of parameters, including drug solubility, skin contact time, lipophilicity,
and permeability. Gels are a relatively new kind of dosage form in which substantial volumes of
aqueous or hydro-alcoholic liquid are entrapped inside a network of colloidal solid particles.
When compared to traditional topical medication delivery formulations, gel formulations allow
quicker drug release. Despite the numerous benefits of gels, one significant drawback is the
difficulty in delivering hydrophobic medicines. Emulgels are created to circumvent these
constraints. Emulgels are now being utilised to administer analgesics, anti-inflammatory, anti-
fungal, anti-acne medicines, and a variety of cosmetic formulations, with a lot more potential.