Unveiling the anti-inflammatory and wound-healing potential of Hedyotis purpurascens through integrated phytochemical and computational evaluation

Abstract

Medicinal plants are prolific sources of bioactive compounds with therapeutic potential for combating
inflammation and promoting wound healing. Hedyotis purpurascens (Rubiaceae) is an ethnomedicinal plant
from the Southern Western Ghats that remains underexplored for its phytochemical composition and
pharmacological relevance. In the present study, the ethanolic leaf extract of H. purpurascens was
subjected to gas chromatography-mass spectrometry (GC-MS) analysis to profile its phytochemical
constituents, followed by in silico molecular docking to evaluate the anti-inflammatory and wound-healing
potential of the identified compounds.