Formulation and Evaluation of a Biocompatible Natural Sunscreen Cream Containing Compritol 888 ATO and Essential Oils

Abstract

 Background: Natural sunscreens are increasingly preferred due to their biocompatibility, antioxidant activity, and safety for sensitive skin. Plant-based oils and mineral ultraviolet filters offer multifunctional benefits and broad-spectrum protection, aligning with current demands for eco-friendly skincare.

Objective: To formulate and evaluate a stable, natural sunscreen cream using Compritol 888 ATO, carrot seed oil, rosemary essential oil, and zinc oxide for enhanced photoprotection and skin compatibility.
Methods: Three formulations (F1, F2, F3) were prepared with varying concentrations of natural actives. Evaluation included pH, spread ability, viscosity, stability, irritancy, and washability. In-vitro sun protection factor values were determined using Mansur’s method, measuring ultraviolet absorbance from 290 to 320nm.

Results: All formulations had skin-compatible pH (6.2-6.6), smooth texture, and good spread ability (up to 14.9 g.cm/sec). No irritation or rancidity was observed. F3, the optimized formulation, showed the highest viscosity (16,950 cP), best stability, and an SPF of 13.82. The synergistic effects of carrot seed and rosemary essential oils, rich in natural antioxidants, along with zinc oxide’s broad-spectrum blocking ability, contributes to improved ultraviolet protection. Compritol 888 ATO played a critical role in emulsion stability and enhanced application.
Conclusions: The developed natural sunscreen cream demonstrated excellent photoprotective efficacy, physicochemical stability, and biocompatibility. These findings support the use of natural oils and mineral filters in effective, skin-safe, and sustainable sun care products.

KEYWORDS

Natural sunscreen, sun protection factor, carrot seed oil, rosemary essential oil, Compritol 880 ATO, zinc oxide, photoprotection.