SIGNIFICANCE OF IMMUNE-INFLAMMATORY PROCESSES IN ASEPTIC NECROSIS OF THE FEMORAL HEAD IN PATIENTS WITH RHEUMATOID ARTHRITIS

Abstract

This article presents data on clinical manifestations and immunological parameters of patients with rheumatoid arthritis accompanied by aseptic necrosis of the femoral head. The results of studies have shown that clinical manifestations of the joint syndrome and immuno-inflammatory processes in RA with ANGBC have their own peculiarities. This is reflected in the aggressiveness of the joint syndrome, rapid progression of radiological changes against the background of persistent activity. RA with ANGBC is accompanied by suppression of T- and B-cell immunity on the background of which there is hyperexpression of proinflammatory cytokines.