EFFECT OF IMIDACLOPRID ON THE BIOCHEMICAL CONTENTS OF KIDNEYS IN MALE SWISS ALBINO MICE

Abstract

Six groups (A, B, C, D, E and F) of male Swiss albino mice (Mus musculus albinus) were orally administered with varied doses (0.4, 0.8, 1.6, 3.2, 4.0 and 8.0 mg/kg bw/mouse) of imidacloprid; they showed significant decrease in protein, DNA and RNA content in the kidneys of all the treated groups of mice throughout the experimental period (on day 1, 4, 8, 12, 16 and 30 of treatment) when compared with controls. It is clear from the results that the insecticide caused marked disturbance in the metabolism of protein, DNA and RNA.