EFFECT OF ETHANOLIC EXTRACT OF PARTHENIUM HYSTEROPHORUS ON HAEMATOLOGICAL PARAMETERS IN RAT

Abstract

Haematological parameters, such as erythrocyte and leukocyte count, hemoglobin concentration, lymphocyte and neutrophil percentage of blood has been considered as bioindicators of toxicosis in animals exposed to xenobiotics. Ethanolic extract of the plant of Parthenium hysterophorus at sub lethal dose, 200 and 400 mg/kg body weight dose when tested against rats in the laboratory reveals a significant decrease in erythrocyte count, hemoglobin concentration, lymphocyte percentage and increase in neutrophil percentage and leukocyte count with respect to time and dose.