A SENSITIVE SPECTROPHOTOMETRIC DETERMINATION OF CENTBUCRIDINE HYDROCHLORIDE IN BULK DRUG & PHAMACEUTICAL FORMULATIONS

V. V. PANDE; S. A. POLSHETTIWAR; J.G. CHANDORKAR; V. V. CHOPADE; A.R. TEKADE; N.M. GOWEKAR

A SENSITIVE SPECTROPHOTOMETRIC DETERMINATION OF CENTBUCRIDINE HYDROCHLORIDE IN BULK DRUG & PHAMACEUTICAL FORMULATIONS

Authors

V. V. PANDE
S. A. POLSHETTIWAR
J.G. CHANDORKAR
V. V. CHOPADE
A.R. TEKADE
N.M. GOWEKAR

Keywords:

Recovery, Assay, Spectrophotometric, Centbucridine

Abstract

A new, simple, sensitive Spectrophotometric method in ultraviolet region has been developed for the determination of Centbucridine hydrochloride in bulk and in dosage form. Centbucridine Hydrochloride shows maximum absorbance at 247 nm with apparent molar absorptivity of 1.0781 X 104 l/mol.cm. Beers law was obeyed in the concentration range of 5 to 50 µg/ml. Results of analysis were validated statistically and by recovery studies. The developed method was found to be sensitive, accurate, precise and reproducible and can be used for the routine quality control analysis of Centbucridine.

Downloads

Published

2007-01-07

How to Cite

V. V. PANDE, S. A. POLSHETTIWAR, J.G. CHANDORKAR, V. V. CHOPADE, A.R. TEKADE, & N.M. GOWEKAR. (2007). A SENSITIVE SPECTROPHOTOMETRIC DETERMINATION OF CENTBUCRIDINE HYDROCHLORIDE IN BULK DRUG & PHAMACEUTICAL FORMULATIONS. The Bioscan, 2(1), 55–56. Retrieved from https://thebioscan.com/index.php/pub/article/view/13